Alison L. Fitzgerald

<i>TP53</i> Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence

Heath D. Skinner, Vlad C. Sandulache, Thomas J. Ow et al. · Clinical Cancer Research · 2011 · 310 citations · Full text

Medicine, Cancer Biology, Oncology +16

Gain-of-Function Mutant p53 Promotes Cell Growth and Cancer Cell Metabolism via Inhibition of AMPK Activation

Ge Zhou, Jiping Wang, Mei Zhao et al. · Molecular Cell · 2014 · 233 citations

Medicine, Cancer Biology, Cell Biology +13

Chk1/2 Inhibition Overcomes the Cisplatin Resistance of Head and Neck Cancer Cells Secondary to the Loss of Functional p53

Mayur A. Gadhikar, Maria Rita Sciuto, Marcus V. Ortega Alves et al. · Molecular Cancer Therapeutics · 2013 · 126 citations · Full text

Medicine, Molecular Biology, Oncology +16

Wee-1 Kinase Inhibition Overcomes Cisplatin Resistance Associated with High-Risk <i>TP53</i> Mutations in Head and Neck Cancer through Mitotic Arrest Followed by Senescence

Abdullah A. Osman, Marcus M. Monroe, Marcus V. Ortega Alves et al. · Molecular Cancer Therapeutics · 2014 · 112 citations

Medicine, Oncology, Pharmacology +15

Reactive oxygen species and p21Waf1/Cip1 are both essential for p53-mediated senescence of head and neck cancer cells

Alison L. Fitzgerald, Abdul-Halim Osman, T-X Xie et al. · Cell Death and Disease · 2015 · 79 citations · Full text

Medicine, Oncology, Radiation Oncology +17