Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in <i>Streptomyces</i> <i>avermitilis</i>

Haruo Ikeda, Tomoko Nonomiya, Masayo Usami, +2

Proceedings of the National Academy of Sciences

Sequence of gene choB encoding cholesterol oxidase of Brevibacterium sterolicum: comparison with choA of Streptomyces sp. SA-COO

Toshio Ohta, Kinya Fujishiro, Yamaguchi Kazuo, +4

Gene

Cholesterol OxidaseBiosynthesisGene ChobBiochemistryBacteriology +5

Fucose content of monoclonal antibodies can be controlled by culture medium osmolality for high antibody-dependent cellular cytotoxicity

Yoshinobu Konno, Y. Kobayashi, Ken L. Takahashi, +10

Cytotechnology

AllergyMedicineImmunologyAntibody ScreeningMonoclonal Antibodies +5

Organization and nature of fortimicin A (astromicin) biosynthetic genes studied using a cosmid library of Micromonospora olivasterospora DNA

Tohru Dairi, Toshio Ohta, Eri Hashimoto, +1

Molecular and General Genetics MGG

BiosynthesisFortimicin AEngineeringBiotransformationBiochemical Taxonomy +7

Purification and properties of a new<i>Brevibacterium sterolicum</i>cholesterol oxidase produced by<i>E. coli</i>MM294/pnH10

Kinya Fujishiro, Hiroyuki Uchida, Kotaro Shimokawa, +6

FEMS Microbiology Letters

Cholesterol OxidaseBiosynthesisEngineeringBiotransformationBiochemistry +8

Acetylpolyamine amidohydrolase from Mycoplana ramosa: gene cloning and characterization of the metal-substituted enzyme

Kazuhiro Sakurada, Toshio Ohta, Kinya Fujishiro, +2

Journal of Bacteriology

Acetylpolyamine AmidohydrolaseBiosynthesisEngineeringCellular EnzymologyBiochemistry +13

Cloning, expression, and characterization of the Micromonospora viridifaciens neuraminidase gene in Streptomyces lividans

Kazuhiro Sakurada, Toshio Ohta, M Hasegawa

Journal of Bacteriology

BiologyMicromonospora Viridifaciens NeuraminidaseNeuraminidase GeneBiosynthesisEngineering +12

Self cloning in Micromonospora olivasterospora of fms genes for fortimicin A (astromicin) biosynthesis

Tohru Dairi, Toshio Ohta, Eri Hashimoto, +1

Molecular and General Genetics MGG

BiologyBiosynthesisFortimicin AFms GenesEngineering +6

Analysis of the self-defense gene (fmrO) of a fortimicin A (astromicin) producer, Micromonospora olivasterospora: comparison with other aminoglycoside-resistance-encoding genes

Toshio Ohta, Mamoru Hasegawa

Gene

BiologyDrug Resistance AnalysisFortimicin ASelf-defense GeneAntimicrobial Resistance Gene +8

Cloning of the gene encoding avermectin B 5-O-methyltransferase in avermectin-producing Streptomyces avermitilis

Haruo Ikeda, Liru Wang, Toshio Ohta, +2

Gene

BiologyAvermectin-producing StreptomycesBiosynthesisEngineeringBiotransformation +6