The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock

Ezra Aksoy, Salma Taboubi, David Torres, +10

Nature Immunology

InflammationSignal TransductionSignaling PathwayCell RegulationApoptosis +10

Monophosphoryl Lipid A Activates Both Human Dendritic Cells and T Cells

Jamila Ismaili, Joëlle Rennesson, Ezra Aksoy, +6

The Journal of Immunology

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR

Denis A. Mogilenko, Joel T. Haas, Laurent L’homme, +37

Cell

InflammationHost ResponseAllergyAutoimmune DiseaseInnate Immune System +9

Double-stranded RNAs from the Helminth Parasite Schistosoma Activate TLR3 in Dendritic Cells

Ezra Aksoy, Claudia S. Zouain, François Vanhoutte, +9

Journal of Biological Chemistry

Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-κB activation and IFN-β synthesis downstream of Toll-like receptor 3 and 4

Ezra Aksoy, Wim Vanden Berghe, Sophie Detienne, +5

European Journal of Immunology

Expression of c-FLIPL and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisindolylmaleimide

Fabienne Willems, Zoulikha Amraoui, Nathalie Vanderheyde, +6

Blood

Expression of c-FLIPL and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisindolylmaleimide

Fabienne Willems, Zoulikha Amraoui, Nathalie Vanderheyde, +6

Blood

Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation

Natalia Reglero-Real, Lorena Pérez, Azumi Yoshimura, +22

Immunity

Endothelial CellsImmunologyEc AutophagyInflammationEndothelial Junctions +14

Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells

Ezra Aksoy, Valentina Albarani, Muriel Nguyen, +6

Blood

Bordetella pertussis toxin induces the release of inflammatory cytokines and dendritic cell activation in whole blood: impaired responses in human newborns

Sandrine Tonon, Stanislas Goriely, Ezra Aksoy, +6

European Journal of Immunology

Innate Immune SystemImmunologyImmunologic MechanismWhole BloodCd4 T Cell Responses +14