Strategies for the Assessment of Protein Aggregates in Pharmaceutical Biotech Product Development

John den Engelsman, Patrick Garidel, Ronald Smulders, +6

Pharmaceutical Research

Immunocytochemical TechniqueImmunologyProtein CharacterizationProtein AggregatesImmunotherapy +21

Tungsten-Induced Denaturation and Aggregation of Epoetin Alfa During Primary Packaging as a Cause of Immunogenicity

Andreas Seidl, Otmar Hainzl, Marleen Richter, +8

Pharmaceutical Research

Shedding of glycan‐modifying enzymes by signal peptide peptidase‐like 3 ( <scp>SPPL</scp> 3) regulates cellular N‐glycosylation

Ulrike Künzel, Fabian Higel, Peer‐Hendrik Kuhn, +12

The EMBO Journal

Operationalised product quality models and assessment: The Quamoco approach

Stefan Wagner, Andreas Goeb, Lars Heinemann, +8

Information and Software Technology

Total Quality ManagementCustomer SatisfactionBusinessQuality CharacteristicImproved Product Quality +3

Efficient projection orders for CAD

Andreas Dolzmann, Andreas Seidl, Thomas Sturm

Mathematical ProgrammingEngineeringComputational ComplexityComputer-aided DesignCylindrical Algebraic Decomposition +15

RAMSIS - A New CAD-Tool for Ergonomic Analysis of Vehicles Developed for the German Automotive Industry

Andreas Seidl

SAE technical papers on CD-ROM/SAE technical paper series

Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90

Edgar E. Boczek, Lasse G. Reefschläger, Marco Dehling, +5

Proceedings of the National Academy of Sciences

Reversed-phase liquid-chromatographic mass spectrometric N-glycan analysis of biopharmaceuticals

Fabian Higel, Uwe Demelbauer, Andreas Seidl, +1

Analytical and Bioanalytical Chemistry

Fluorescent LabelGlycobiologyBiological Mass SpectrometryBioanalysisImmunochemistry +15

N-glycans of complex glycosylated biopharmaceuticals and their impact on protein clearance

Fabian Higel, Theresa Sandl, Chi-Ya Kao, +4

European Journal of Pharmaceutics and Biopharmaceutics

Immunocytochemical TechniqueGlycobiologyImmunologyPolysaccharideImmunotherapy +17

Rational Selection, Criticality Assessment, and Tiering of Quality Attributes and Test Methods for Analytical Similarity Evaluation of Biosimilars

Kristof Vandekerckhove, Andreas Seidl, Hiten Gutka, +5

The AAPS Journal

Stepwise FashionAnalytical Similarity EvaluationEngineeringVerification And ValidationQuality Evaluation +16