Ryo Tatsumi

Discovery of the α7 Nicotinic Acetylcholine Receptor Agonists. (<i>R</i>)-3‘-(5-Chlorothiophen-2-yl)spiro-1-azabicyclo[2.2.2]octane-3,5‘-[1‘,3‘]oxazolidin-2‘-one as a Novel, Potent, Selective, and Orally Bioavailable Ligand

Ryo Tatsumi, Masakazu Fujio, Hiroyuki Satoh et al. · Journal of Medicinal Chemistry · 2005 · 46 citations · Full text

Orally Bioavailable Ligand, Pharmacotherapy, Pharmaceutical Chemistry +19

(<i>R</i>)-3‘-(3-Methylbenzo[<i>b</i>]thiophen-5-yl)spiro[1-azabicyclo[2,2,2]octane-3,5‘-oxazolidin]-2‘-one, a Novel and Potent α7 Nicotinic Acetylcholine Receptor Partial Agonist Displays Cognitive Enhancing Properties

Ryo Tatsumi, Masakazu Fujio, Shin-ichi Takanashi et al. · Journal of Medicinal Chemistry · 2006 · 43 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Chemical Optimization +15

A new route for the construction of the AB-ring core of Taxol

Yumi Shimada, Makoto Nakamura, Toshimasa Suzuka et al. · Tetrahedron Letters · 2003 · 25 citations

Ab-ring Core, New Route, Ring Theory

(+)-3-[2-(Benzo[b]thiophen-2-yl)-2-oxoethyl]-1-azabicyclo[2.2.2]octane as potent agonists for the α7 nicotinic acetylcholine receptor

Ryo Tatsumi, Kohji Seio, Masakazu Fujio et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 25 citations · Full text

Synthesis and evaluation of [125I]I-TSA as a brain nicotinic acetylcholine receptor α7 subtype imaging agent

Mikako Ogawa, Ryo Tatsumi, Masakazu Fujio et al. · Nuclear Medicine and Biology · 2006 · 20 citations

Medicine, Neurotransmitter, Receptor (Biochemistry) +4