Jakob Hauge Mikkelsen

Stanniocalcin-2 Inhibits Mammalian Growth by Proteolytic Inhibition of the Insulin-like Growth Factor Axis

Malene R. Jepsen, Søren Kløverpris, Jakob Hauge Mikkelsen et al. · Journal of Biological Chemistry · 2014 · 184 citations · Full text

Life Sciences, Biochemistry, Endocrinology +13

Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A

Søren Kløverpris, Jakob Hauge Mikkelsen, Josefine H. Pedersen et al. · Journal of Biological Chemistry · 2015 · 123 citations · Full text

Medicine, Biochemistry, Medicinal Chemistry +13

Indirect targeting of IGF receptor signaling<i>in vivo</i>by substrate-selective inhibition of PAPP-A proteolytic activity

Jakob Hauge Mikkelsen, Zachary T. Resch, Bhanu Kalra et al. · Oncotarget · 2014 · 58 citations · Full text

Medicine, Endocrinology, Oncology +15

Inhibition of the Proteolytic Activity of Pregnancy-associated Plasma Protein-A by Targeting Substrate Exosite Binding

Jakob Hauge Mikkelsen, Claus Gyrup, Peter Kristensen et al. · Journal of Biological Chemistry · 2008 · 47 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism

Sara Dam Kobberø, Michael Gajhede, Osman Mirza et al. · Nature Communications · 2022 · 32 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16