Group B streptococci escape host immunity by deletion of tandem repeat elements of the alpha C protein.

Lawrence C. Madoff, J L Michel, E W Gong, +2

Proceedings of the National Academy of Sciences

Maternal IsolatesMicrobial PathogensImmunologyAlpha C ProteinMaternal Immunization +14

Large, identical, tandem repeating units in the C protein alpha antigen gene, bca, of group B streptococci.

J L Michel, Lawrence C. Madoff, Kristine C. Olson, +3

Proceedings of the National Academy of Sciences

Medical MicrobiologyBca LocusGroup BMedicineGroup B Streptococci +11

Mosaicism in the alpha-like protein genes of group B streptococci

Catherine S. Lachenauer, Roberta Creti, J L Michel, +1

Proceedings of the National Academy of Sciences

GeneticsBacteriologyMolecular GeneticsHorizontal Dna TransferGenomics +15

Cloned alpha and beta C-protein antigens of group B streptococci elicit protective immunity

J L Michel, Lawrence C. Madoff, David E. Kling, +2

Infection and Immunity

VaccinationMedical MicrobiologyNeonatal SepsisRestriction Enzyme AnalysisAntimicrobial Resistance Gene +13

A monoclonal antibody identifies a protective C-protein alpha-antigen epitope in group B streptococci

Lawrence C. Madoff, J L Michel, Dennis L. Kasper

Infection and Immunity

VaccinationMicrobial PathogensVaccine TargetGroup B StreptococciPathogenesis +13

Inactivation of the α C protein antigen gene,<i>bca</i>, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B <i>Streptococcus</i>

Jing Li, Dennis L. Kasper, Frederick M. Ausubel, +2

Proceedings of the National Academy of Sciences

Variation in repeat number within the alpha C protein of group B streptococci alters antigenicity and protective epitopes

Claudia Gravekamp, Debra S. Horensky, J L Michel, +1

Infection and Immunity

VaccinationProtective EpitopesVaccine DevelopmentVaccine TargetRepeat Number +13

Protection of neonatal mice from group B streptococcal infection by maternal immunization with beta C protein

Lawrence C. Madoff, J L Michel, E W Gong, +2

Infection and Immunity

Phenotypic diversity in the alpha C protein of group B streptococci

Lawrence C. Madoff, Shohei Hori, J L Michel, +2

Infection and Immunity

Group B StreptococciBacteriologyImmunologyAntigen ProcessingAlpha C Protein +15

Evidence that the regulation of diphtheria toxin production is directed at the level of transcription

J R Murphy, J L Michel, Mingxiang Teng

Journal of Bacteriology

ToxinologyGeneticsBacteriologyMolecular BiologyTranscriptional Regulation +18