Kunihiko Ikeguchi

A Phase I Study of Aromatic L-Amino Acid Decarboxylase Gene Therapy for Parkinson's Disease

Shin‐ichi Muramatsu, Kenichi Fujimoto, Seiya Kato et al. · Molecular Therapy · 2010 · 335 citations · Full text

Neuroprotective Effects of Glial Cell Line-Derived Neurotrophic Factor Mediated by an Adeno-Associated Virus Vector in a Transgenic Animal Model of Amyotrophic Lateral Sclerosis

Lijun Wang, Yanyan Lu, Shin‐ichi Muramatsu et al. · Journal of Neuroscience · 2002 · 267 citations · Full text

Triple Transduction with Adeno-Associated Virus Vectors Expressing Tyrosine Hydroxylase, Aromatic-L-Amino-Acid Decarboxylase, and GTP Cyclohydrolase I for Gene Therapy of Parkinson's Disease

Yang Shen, Shin‐ichi Muramatsu, Kunihiko Ikeguchi et al. · Human Gene Therapy · 2000 · 194 citations

Aldehyde Dehydrogenase, Biochemistry, Medicine +15

Behavioral Recovery in a Primate Model of Parkinson's Disease by Triple Transduction of Striatal Cells with Adeno-Associated Viral Vectors Expressing Dopamine-Synthesizing Enzymes

Shin‐ichi Muramatsu, Ken-ichi Fujimoto, Kunihiko Ikeguchi et al. · Human Gene Therapy · 2002 · 185 citations

Primate Model, Medicine, Functional Selectivity +15

Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease

Lijun Wang, Shin‐ichi Muramatsu, Yanyan Lu et al. · Gene Therapy · 2002 · 156 citations · Full text

Neurodegenerative Diseases, Neuroregeneration, Functional Recovery +8