Daniel K. Afosah

Molecular principles for heparin oligosaccharide–based inhibition of neutrophil elastase in cystic fibrosis

Apparao B. Kummarapurugu, Daniel K. Afosah, Nehru Viji Sankaranarayanan et al. · Journal of Biological Chemistry · 2018 · 41 citations · Full text

Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin

Stephen Verespy, Akul Y. Mehta, Daniel K. Afosah et al. · Scientific Reports · 2016 · 36 citations · Full text

A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding

Rami A. Al‐Horani, Elsamani I. Abdelfadiel, Daniel K. Afosah et al. · Journal of Thrombosis and Haemostasis · 2019 · 33 citations · Full text

Inflammation, Thrombosis, Reduces Thrombosis +15

2-O, 3-O Desulfated Heparin Blocks High Mobility Group Box 1 Release by Inhibition of p300 Acetyltransferase Activity

Shuo Zheng, Apparao B. Kummarapurugu, Daniel K. Afosah et al. · American Journal of Respiratory Cell and Molecular Biology · 2016 · 31 citations · Full text

Inflammatory Lung Disease, Lung Inflammation, Immunology +16

Potent, Selective, Allosteric Inhibition of Human Plasmin by Sulfated Non-Saccharide Glycosaminoglycan Mimetics

Daniel K. Afosah, Rami A. Al‐Horani, Nehru Viji Sankaranarayanan et al. · Journal of Medicinal Chemistry · 2016 · 31 citations · Full text

Pharmaceutical Science, Allosteric Inhibition, Glycobiology +21