RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications

Mayte Suárez‐Fariñas, Benjamin Ungar, Joel Corrêa da Rosa, +10

Journal of Allergy and Clinical Immunology

BioinformaticsAutoimmune DiseaseAtopic DermatitisMedicineNovel Disease Mechanisms +10

Guanine nucleotide-binding protein Go-induced coupling of neuropeptide Y receptors to Ca2+ channels in sensory neurons.

David Ewald, Paul C. Sternweis, R J Miller

Proceedings of the National Academy of Sciences

Neuropeptide Y ReceptorsSensory NeuronsNeurotransmitterMolecular BiologyNeurotransmission +20

Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.

Maurine E. Linder, David Ewald, R J Miller, +1

Journal of Biological Chemistry

BacteriologyMolecular BiologyEscherichia ColiPertussis ToxinCellular Physiology +18

Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection

Hitokazu Esaki, David Ewald, Benjamin Ungar, +10

Journal of Allergy and Clinical Immunology

Barrier GenesAtopic DermatitisImmunologySkin AllergyLaser Capture Microdissection +6

Differential bacterial capture and transport preferences facilitate co-growth on dietary xylan in the human gut

Maria Louise Leth, Morten Ejby, Christopher T. Workman, +8

Nature Microbiology

NutritionDysbiosisHost-microbe InteractionsDigestive TractDifferential Bacterial Capture +14

Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling

David Ewald, Shinji Noda, Margeaux Oliva, +12

Journal of Allergy and Clinical Immunology

Functional GenomicsAllergyAtopic DermatitisHuman Atopic DermatitisComputational Biology +9

Short-term transcriptional response to IL-17 receptor-A antagonism in the treatment of psoriasis

Lewis E. Tomalin, Chris B. Russell, Sandra Garcet, +6

Journal of Allergy and Clinical Immunology

InflammationCytokineAutoimmune DiseaseMedicineImmunology +8

Signalling of multiple interleukin (IL)‐17 family cytokines via IL‐17 receptor A drives psoriasis‐related inflammatory pathways

Maxim A. X. Tollenaere, Josephine B. Hebsgaard, David Ewald, +8

British Journal of Dermatology

Assessment of Spatial and Temporal Variation in the Skin Transcriptome of Atopic Dermatitis by Use of 1.5 mm Minipunch Biopsies

Tu Hu, Tanja Todberg, David Ewald, +4

Journal of Investigative Dermatology

Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment

Stefan Eirefelt, Martin Stahlhut, Naila Svitacheva, +9

Scientific Reports