Concepedia

Pierre Nimsgern

PN

3

Publications

189

Citations

3

H-Index

2020

Active since

Affiliations

Novartis (Switzerland)(Current)

Genomics Institute of the Novartis Research Foundation

Novartis Institutes for BioMedical Research

Pierre Nimsgern is an author at Novartis (Switzerland) specializing in biomolecular engineering, drug discovery, and small molecules.

Top concepts

Biomolecular EngineeringMedicineEngineeringCell BiologyPharmacologyCell SignalingDrug DiscoveryDna ReplicationSmall MoleculesChemical Biology

Publications per year

2020–2020

3

Publications

3

Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4

Robin A. Fairhurst, Thomas Knoepfel, Nicole Buschmann et al. · Journal of Medicinal Chemistry · 2020 · 106 citations · Full text

Reversible-covalent Inhibitor, Molecular Pharmacology, Signaling Pathway +19

An Amphiphilic Polymer-Supported Strategy Enables Chemical Transformations under Anhydrous Conditions for DNA-Encoded Library Synthesis

Yves Ruff, Roberto Martı́nez, Xavier Pellé et al. · ACS Combinatorial Science · 2020 · 58 citations · Full text

Combinatorial Chemistry, Engineering, Dna-encoded Library Synthesis +20

Target-Based Identification and Optimization of 5-Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists Using a Biochemical TLR8 Antagonist Competition Assay

Thomas Knoepfel, Pierre Nimsgern, Sébastien Jacquier et al. · Journal of Medicinal Chemistry · 2020 · 25 citations · Full text

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