Bisphenol A Induces Gene Expression Changes and Proliferative Effects through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts

Marco Pupo, Assunta Pisano, Rosamaria Lappano, +5

Environmental Health Perspectives

G Protein-coupled Estrogen Receptor Mediates the Up-regulation of Fatty Acid Synthase Induced by 17β-Estradiol in Cancer Cells and Cancer-associated Fibroblasts

Maria Francesca Santolla, Rosamaria Lappano, Paola De Marco, +8

Journal of Biological Chemistry

MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells

Rosamaria Lappano, Maria Francesca Santolla, Marco Pupo, +4

Breast Cancer Research

Two Novel GPER Agonists Induce Gene Expression Changes and Growth Effects in Cancer Cells

Rosamaria Lappano, Camillo Rosano, Maria Francesca Santolla, +7

Current Cancer Drug Targets

GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response

Paola De Marco, Rosamaria Lappano, Ernestina Marianna De Francesco, +7

Scientific Reports

The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs)

Marco Pupo, Adele Vivacqua, Ida Perrotta, +6

Molecular and Cellular Endocrinology

Nuclear Gper TranslocationBreast OncologyMedicineNuclear Localization SignalBreast Cancer-associated Fibroblasts +9

GPER activates Notch signaling in breast cancer cells and cancer-associated fibroblasts (CAFs)

Marco Pupo, Assunta Pisano, Sergio Abonante, +2

The International Journal of Biochemistry & Cell Biology

Breast OncologySignaling PathwayMedicineBreast Cancer CellsCancer-associated Fibroblasts +9

GPER Mediates Cardiotropic Effects in Spontaneously Hypertensive Rat Hearts

Ernestina Marianna De Francesco, Tommaso Angelone, Teresa Pasqua, +3

PLoS ONE

HypertensionEstrogen ReceptorEstrogenic SignalingFemale Reproductive FunctionCardiovascular Function +22

GPER Mediates Non-Genomic Effects of Estrogen

Marco Pupo, Marcello Maggiolini, Anna Maria Musti

Methods in molecular biology

Hormonal ReceptorGeneticsMenopauseEndocrinologyMedicine +3

A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells

Marco Pupo, Alexandre Bodmer, Mélissa Berto, +3

Oncotarget

Breast OncologyGeneticsCancer BiologyTumor BiologyGper P16l Polymorphism +16