David S. Umbaugh

Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice

Nga Nguyen, Kuo Du, Jephte Y. Akakpo et al. · Toxicology Letters · 2020 · 68 citations · Full text

Reductive Stress, Superoxide Generation, Biochemistry +13

Kupffer cells regulate liver recovery through induction of chemokine receptor CXCR2 on hepatocytes after acetaminophen overdose in mice

Nga Nguyen, David S. Umbaugh, Giselle Sánchez-Guerrero et al. · Archives of Toxicology · 2021 · 49 citations · Full text

Inflammation, Hepatology, Medicine +13

Mitochondrial Membrane Potential Drives Early Change in Mitochondrial Morphology After Acetaminophen Exposure

David S. Umbaugh, Nga Nguyen, Hartmut Jaeschke et al. · Toxicological Sciences · 2021 · 44 citations · Full text

Spatial Reconstruction of the Early Hepatic Transcriptomic Landscape After an Acetaminophen Overdose Using Single-Cell RNA-Sequencing

David S. Umbaugh, Anup Ramachandran, Hartmut Jaeschke · Toxicological Sciences · 2021 · 37 citations · Full text

Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice

Nga Nguyen, David S. Umbaugh, Sawyer Smith et al. · Archives of Toxicology · 2023 · 36 citations · Full text

Inflammation, Anti-inflammatory, Hepatology +13