Silibinin inhibits acetylcholinesterase activity and amyloid β peptide aggregation: a dual-target drug for the treatment of Alzheimer’s disease

Songwei Duan, Xiaoyin Guan, Runxuan Lin, +12

Neurobiology of Aging

Neurodegenerative DiseasesAlzheimer's DiseaseDual-target DrugAcetylcholinesterase ActivityMedicine +9

WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

Sixian Qi, Yuwen Zhu, Xincheng Liu, +16

Molecular Cell

Signal TransductionSignaling PathwayMedicineReceptor Tyrosine KinaseProtein Phosphorylation +8

MTHFD2 Overexpression Predicts Poor Prognosis in Renal Cell Carcinoma and is Associated with Cell Proliferation and Vimentin-Modulated Migration and Invasion

Hao Lin, Bin Huang, Hua Wang, +4

Cellular Physiology and Biochemistry

Functional regeneration of ligament-bone interface using a triphasic silk-based graft

Hongguo Li, Jiabing Fan, Liguo Sun, +3

Biomaterials

Tissue EngineeringRegenerative MedicineEngineeringBone RepairOsteoarthritis +8

TPX2 Level Correlates with Hepatocellular Carcinoma Cell Proliferation, Apoptosis, and EMT

Bo Liang, Chunhong Jia, Yu Huang, +7

Digestive Diseases and Sciences

Tumor BiologyHepatologyTpx2 Level CorrelatesMedicineLiver Physiology +10

Methylenetetrahydrofolate dehydrogenase 2 overexpression is associated with tumor aggressiveness and poor prognosis in hepatocellular carcinoma

Xincheng Liu, Yu Huang, Chenglong Jiang, +5

Digestive and Liver Disease

HepatologyOncogenic AgentMedicinePathologyPoor Prognosis +9

R406 elicits anti-Warburg effect via Syk-dependent and -independent mechanisms to trigger apoptosis in glioma stem cells

Shuxin Sun, Dongdong Xue, Zhijie Chen, +16

Cell Death and Disease

Effects of Mechanical Stretch on Cell Proliferation and Matrix Formation of Mesenchymal Stem Cell and Anterior Cruciate Ligament Fibroblast

Liguo Sun, Ling Qu, Rui Zhu, +5

Stem Cells International

Tissue EngineeringEngineeringCell ProliferationBiomedical EngineeringOrthopaedic Surgery +21

Dramatic antitumor effects of the dual mTORC1 and mTORC2 inhibitor AZD2014 in hepatocellular carcinoma.

Hui Liao, Yu Huang, Botang Guo, +6

PubMed

Mtor AxisChemoprevention StrategyImmunologyTumor BiologyOncology +17

Intravenous injection of the oncolytic virus M1 awakens antitumor T cells and overcomes resistance to checkpoint blockade

Yang Liu, Jing Cai, Wenfeng Liu, +10

Cell Death and Disease