Paul Najm

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination

Mikhail Steklov, Silvia Pandolfi, Maria Francesca Baietti et al. · Science · 2018 · 218 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Stress-induced lncRNA LASTR fosters cancer cell fitness by regulating the activity of the U4/U6 recycling factor SART3

Linde De Troyer, Peihua Zhao, Tibor J. Pastor et al. · Nucleic Acids Research · 2020 · 51 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Loss-of-Function Mutations in TRAF7 and KLF4 Cooperatively Activate RAS-Like GTPase Signaling and Promote Meningioma Development

Paul Najm, Peihua Zhao, Mikhail Steklov et al. · Cancer Research · 2021 · 35 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

Efficient shRNA-based knockdown of multiple target genes for cell therapy using a chimeric miRNA cluster platform

Matteo Rossi, Mikhail Steklov, Fanny Huberty et al. · Molecular Therapy — Nucleic Acids · 2023 · 24 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +13

β-2-himachalen-6-ol: A novel anticancer sesquiterpene unique to the Lebanese wild carrot

Robin I. Taleb, Paul Najm, Wassim N. Shebaby et al. · Journal of Ethnopharmacology · 2016 · 17 citations

Pharmacy, Medicinal Chemistry, Oncology +11