George L. Sutphin

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

Camilla Burnett, Sara Valentini, Filipe Cabreiro et al. · Nature · 2011 · 623 citations · Full text

Education, Genetics, Molecular Genetics +7

Dietary restriction suppresses proteotoxicity and enhances longevity by an <i>hsf‐1</i> ‐dependent mechanism in <i>Caenorhabditis elegans</i>

Katherine A. Steinkraus, Erica D. Smith, Christina Davis et al. · Aging Cell · 2008 · 272 citations · Full text

Medicine, Neurobiology, Neuroscience +14

A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging

Mark A. McCormick, Joe R. Delaney, Mitsuhiro Tsuchiya et al. · Cell Metabolism · 2015 · 270 citations · Full text

Education, Genetics, Molecular Genetics +12

Proteasomal Regulation of the Hypoxic Response Modulates Aging in <i>C. elegans</i>

Ranjana Mehta, Katherine A. Steinkraus, George L. Sutphin et al. · Science · 2009 · 246 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae

Undine Kruegel, Brett Robison, Thomas Dange et al. · PLoS Genetics · 2011 · 243 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16