Daisy F. Rangel

GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant <i>Kras</i> -driven pancreatic tumorigenesis in mice

Jieli Shen, Dat P. Ha, Genyuan Zhu et al. · Proceedings of the National Academy of Sciences · 2017 · 53 citations · Full text

Suppression of stress induction of the 78-kilodalton glucose regulated protein (GRP78) in cancer by IT-139, an anti-tumor ruthenium small molecule inhibitor

Suzanne J. Bakewell, Daisy F. Rangel, Dat P. Ha et al. · Oncotarget · 2018 · 47 citations · Full text

Systems Biology, Grp78 Expression, 78-Kilodalton Glucose +14

Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis

Daisy F. Rangel, Louis Dubeau, Ryan S. Park et al. · Oncogene · 2021 · 31 citations · Full text

Medicine, Natural Sciences, Molecular Biology +7

Targeting GRP78 suppresses oncogenic KRAS protein expression and reduces viability of cancer cells bearing various KRAS mutations

Dat P. Ha, Bo Huang, Han Wang et al. · Neoplasia · 2022 · 29 citations · Full text

Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice

Amy S. Lee, Sebastian Brandhorst, Daisy F. Rangel et al. · Scientific Reports · 2017 · 15 citations · Full text