Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells

Sofia Appelberg, Soham Gupta, Sara Svensson Akusjärvi, +12

Emerging Microbes & Infections

Δ9-Tetrahydrocannabinol Treatment During Human Monocyte Differentiation Reduces Macrophage Susceptibility to HIV-1 Infection

Julie Williams, Sofia Appelberg, Bruce A. Goldberger, +3

Journal of Neuroimmune Pharmacology

Immune Cell DevelopmentHuman RetrovirusImmunologyImmune RegulationAntiviral Response +7

Crimean–Congo haemorrhagic fever virus uses LDLR to bind and enter host cells

Vanessa Monteil, Shane C. Wright, Matheus Dyczynski, +24

Nature Microbiology

Accelerated DNA vaccine regimen provides protection against Crimean-Congo hemorrhagic fever virus challenge in a macaque model

David W. Hawman, Kimberly Meade‐White, Shanna Leventhal, +10

Molecular Therapy

The HIV-1 protease inhibitor nelfinavir activates PP2 and inhibits MAPK signaling in macrophages: a pathway to reduce inflammation

Mark A. Wallet, Caroline M Reist, Julie Williams, +5

Journal of Leukocyte Biology

ImmunologyImmune RegulationHiv-1 Pi NfvInnate ImmunityScd14 Levels +23

A universal <scp>SARS‐CoV DNA</scp> vaccine inducing highly cross‐reactive neutralizing antibodies and T cells

Sofia Appelberg, Gustaf Ahlén, Jingyi Yan, +17

EMBO Molecular Medicine

VaccinationCross‐reactive Neutralizing AntibodiesVaccine DevelopmentImmunologyT Cell Immunity +6

Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization

Arman Izadi, Arsema Hailu, Magdalena Godzwon, +12

Proceedings of the National Academy of Sciences

Signal TransductionImmune Effector FunctionsAllergySignaling PathwayCell Interaction +11

Hazara virus and Crimean-Congo Hemorrhagic Fever Virus show a different pattern of entry in fully-polarized Caco-2 cell line

Vanessa Monteil, Cristiano Salata, Sofia Appelberg, +1

PLoS neglected tropical diseases

Molecular VirologyCchfv VirusPathogenesisImmunologyViral Pathogenesis +10

Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections

Vanessa Monteil, Hyesoo Kwon, Lijo John, +21

Nature Communications

Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse

Amy Flaxman, Sarah Sebastian, Sofia Appelberg, +15

PLoS Pathogens