Robert A. Farr

Inhibition of Human Neutrophil Elastase. 4. Design, Synthesis, X-ray Crystallographic Analysis, and Structure−Activity Relationships for a Series of P₂-Modified, Orally Active Peptidyl Pentafluoroethyl Ketones

Robert J. Cregge, Sherrie Durham, Robert A. Farr et al. · Journal of Medicinal Chemistry · 1998 · 58 citations · Full text

Synthesis of 1s,2r,3s,4r,5r-methyl[2,3,4-trihydroxy-5-(hydroxymbthyl)cyclopentyl]amine: a potent α-mannosidase inhibitor

Robert A. Farr, Norton P. Peet, Nohinder S. Fang · Tetrahedron Letters · 1990 · 55 citations

Medicinal Chemistry, Medicine, Potent α-Mannosidase Inhibitor +4

Pyrrolidine and hexahydro-1 H-azepine mimics of the ‘flap up’ mannosyl cation

Robert A. Farr, Amy K. Holland, Edward W. Huber et al. · Tetrahedron · 1994 · 46 citations

Bioorganic Chemistry, Engineering, Biochemistry +7

Chemical Development of MDL 103371:  An <i>N</i>-Methyl-<scp>d</scp>-Aspartate-Type Glycine Receptor Antagonist for the Treatment of Stroke

Timothy Watson, Stephen W. Horgan, Ramnik S. Shah et al. · Organic Process Research & Development · 2000 · 35 citations

Pharmaceutical Science, Chemical Development, Mdl 103371 +16

Design, Synthesis, and Conformational Analysis of a Novel Macrocyclic HIV-Protease Inhibitor

Brent L. Podlogar, Robert A. Farr, Dirk Friedrich et al. · Journal of Medicinal Chemistry · 1994 · 31 citations · Full text

Cyclic Inhibitor, Pharmaceutical Chemistry, Medicinal Chemistry +16