Alyson Speed

Fumarate induces vesicular release of mtDNA to drive innate immunity

Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya et al. · Nature · 2023 · 311 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer

Saroor A. Patel, Shoko Hirosue, Paulo Rodrigues et al. · Nature · 2022 · 81 citations · Full text

Medicine, Cell Biology, Molecular Genetics +5

Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity

Frances K. Turrell, Emma Kerr, Meiling Gao et al. · Genes & Development · 2017 · 71 citations · Full text

Medicine, Genetics, Oncology +14

Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues

Marlous Kamp, Jakub Surmacki, Marc Segarra Mondejar et al. · Nature Communications · 2024 · 36 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

<i>HIRA</i> loss transforms <i>FH</i> -deficient cells

Lorea Valcárcel-Jiménez, Connor Rogerson, Cissy Yong et al. · Science Advances · 2022 · 14 citations · Full text

Medicine, Genetics, Oncology +17