Frances K. Turrell

Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities

Emma Kerr, Edoardo Gaude, Frances K. Turrell et al. · Nature · 2016 · 303 citations · Full text

Metabolic Network, Metabolic Reprogramming, Genetics +7

Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity

Frances K. Turrell, Emma Kerr, Meiling Gao et al. · Genes & Development · 2017 · 69 citations · Full text

Age-associated microenvironmental changes highlight the role of PDGF-C in ER+ breast cancer metastatic relapse

Frances K. Turrell, Rebecca Orha, Naomi Guppy et al. · Nature Cancer · 2023 · 69 citations · Full text

Dickkopf-3 regulates prostate epithelial cell acinar morphogenesis and prostate cancer cell invasion by limiting TGF-β-dependent activation of matrix metalloproteases

Diana Romero, Zainab Al Shareef, Irantzu Gorroño‐Etxebarria et al. · Carcinogenesis · 2015 · 35 citations · Full text

Matrix Metalloproteases, Cancer Biology, Tumor Biology +18

Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis

Sarah Ash, Rebecca Orha, Holly Mole et al. · Journal for ImmunoTherapy of Cancer · 2024 · 26 citations · Full text