Concepedia

Adam Oken

AO

Statistics

Publications

5

Citations

86

H-Index

5

Active since

2024

Affiliations

Oregon Health & Science University(Current)

Adam Oken is an author at Oregon Health & Science University specializing in ion channel pharmacology, structural biology, and molecular pharmacology.

ORCID

Publications per year

2024–2025

5

Publications

5

High-affinity agonism at the P2X7 receptor is mediated by three residues outside the orthosteric pocket

Adam Oken, Nicolas E. Lisi, Ipsita Krishnamurthy et al. · Nature Communications · 2024 · 23 citations · Full text

, , +17

P2X <sub>7</sub> receptors exhibit at least three modes of allosteric antagonism

Adam Oken, Ismayn A. Ditter, Nicolas E. Lisi et al. · Science Advances · 2024 · 21 citations · Full text

, , +17

Cryo-EM structures of the human P2X1 receptor reveal subtype-specific architecture and antagonism by supramolecular ligand-binding

Adam Oken, Nicolas E. Lisi, Ismayn A. Ditter et al. · Nature Communications · 2024 · 17 citations · Full text

, , +17

Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket

Haoyuan Shi, Ismayn A. Ditter, Adam Oken et al. · Science Advances · 2025 · 15 citations · Full text

, , +17

A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor

Adam Oken, Andreea L. Turcu, Eva Tzortzini et al. · Nature Communications · 2025 · 10 citations · Full text

, , +17

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