Oral Delivery of Angiotensin-Converting Enzyme 2 and Angiotensin-(1-7) Bioencapsulated in Plant Cells Attenuates Pulmonary Hypertension

Vinayak Shenoy, Kwang‐Chul Kwon, Anandharajan Rathinasabapathy, +11

Hypertension

Pulmonary HypertensionReversal ProtocolOxidative StressPulmonary PharmacologyOral Delivery +14

Oral delivery of bioencapsulated exendin‐4 expressed in chloroplasts lowers blood glucose level in mice and stimulates insulin secretion in beta‐<scp>TC</scp>6 cells

Kwang‐Chul Kwon, Ramya Nityanandam, James S. New, +1

Plant Biotechnology Journal

Cell-based Drug DeliveryChloroplasts LowersGlycosylationBiochemistryMedicine +11

Oral Delivery of ACE2/Ang-(1–7) Bioencapsulated in Plant Cells Protects against Experimental Uveitis and Autoimmune Uveoretinitis

Pollob Shil, Kwang‐Chul Kwon, Ping Zhu, +3

Molecular Therapy

Seedling Lethal1, a Pentatricopeptide Repeat Protein Lacking an E/E+ or DYW Domain in Arabidopsis, Is Involved in Plastid Gene Expression and Early Chloroplast Development

Young Jae Pyo, Kwang‐Chul Kwon, A. Kim, +1

PLANT PHYSIOLOGY

GeneticsMolecular BiologyMolecular GeneticsGenomicsPls Subfamily +14

Release of Proteins from Intact Chloroplasts Induced by Reactive Oxygen Species during Biotic and Abiotic Stress

Kwang‐Chul Kwon, Dheeraj Verma, Shuangxia Jin, +2

PLoS ONE

EngineeringMolecular BiologyPlant BiochemistryReactive Oxygen SpeciesGfp Release +24

Oral delivery of novel human IGF-1 bioencapsulated in lettuce cells promotes musculoskeletal cell proliferation, differentiation and diabetic fracture healing

J. Park, Guo Yan, Kwang‐Chul Kwon, +4

Biomaterials

Tissue EngineeringNovel Human Igf-1EngineeringAntibiotic Resistance GeneBone Repair +19

Codon Optimization to Enhance Expression Yields Insights into Chloroplast Translation

Kwang‐Chul Kwon, Hui‐Ting Chan, Ileana R. León, +3

PLANT PHYSIOLOGY

GeneticsMolecular BiologyProtein SynthesisProteomic TechnologyBiosynthesis +14

A new prokaryotic expression vector for the expression of antimicrobial peptide abaecin using SUMO fusion tag

Da Sol Kim, Seon Woong Kim, Jae Min Song, +2

BMC Biotechnology

Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia A mice

Kwang‐Chul Kwon, Alexandra Sherman, Wan‐Jung Chang, +4

Plant Biotechnology Journal

Low cost delivery of proteins bioencapsulated in plant cells to human non-immune or immune modulatory cells

Yuhong Xiao, Kwang‐Chul Kwon, Brad E. Hoffman, +4

Biomaterials