Alexander S. Wahba

2′-Fluoro-4′-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity

Jonathan K. Watts, Niloufar Choubdar, Kashinath Sadalapure et al. · Nucleic Acids Research · 2007 · 78 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CLpro covalent inhibitors

Julia Stille, Jevgenijs Tjutrins, Guanyu Wang et al. · European Journal of Medicinal Chemistry · 2021 · 76 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

A single-label phenylpyrrolocytidine provides a molecular beacon-like response reporting HIV-1 RT RNase H activity

Alexander S. Wahba, Abbas Ali Esmaeili, Masad J. Damha et al. · Nucleic Acids Research · 2009 · 54 citations · Full text

Life Sciences, Biology, Molecular Biology +16

Phenylpyrrolocytosine as an Unobtrusive Base Modification for Monitoring Activity and Cellular Trafficking of siRNA

Alexander S. Wahba, Fereshteh Azizi, Glen F. Deleavey et al. · ACS Chemical Biology · 2011 · 50 citations

Life Sciences, Cell Biology, Molecular Biology +17

Synthesis and Biophysical Characterization of Oligonucleotides Containing a 4′-Selenonucleotide

Jonathan K. Watts, Blair D. Johnston, Kumarasamy Jayakanthan et al. · Journal of the American Chemical Society · 2008 · 47 citations

Life Sciences, Biochemistry, Molecular Biology +17