Laurence J. Seabrook

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Active since

2021

Affiliations

University of California, Los Angeles(Current)

University of California, Irvine

Laurence J. Seabrook is an author at University of California, Los Angeles specializing in ubiquitin-mediated degradation, proteasome system, and protein degradation.

ORCID

Publications per year

2021–2025

Publications

Methylarginine targeting chimeras for lysosomal degradation of intracellular proteins

Laurence J. Seabrook, Carolina N. Franco, Cody A. Loy et al. · Nature Chemical Biology · 2024 · 25 citations

Life Sciences, Biochemistry, Molecular Biology +14

ByeTAC: Bypassing E-Ligase-Targeting Chimeras for Direct Proteasome Degradation

Cody A. Loy, Eslam M.H. Ali, Laurence J. Seabrook et al. · Journal of Medicinal Chemistry · 2025 · 19 citations

Life Sciences, Biochemistry, Molecular Biology +15

Vitamin B <sub>6</sub> is governed by the local compartmentalization of metabolic enzymes during growth

Carolina N. Franco, Laurence J. Seabrook, Steven T. Nguyen et al. · Science Advances · 2023 · 12 citations · Full text

Medicine, Cancer Biology, Oncology +17

Asymmetric organelle positioning during epithelial polarization of C. elegans intestinal cells

James N. Brandt, Laura Voss, Fiona M. Rambo et al. · Developmental Biology · 2021 · 11 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

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