Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS

Line S. Reinert, Katarína Lopušná, Henriette Winther, +9

Nature Communications

Innate Immune SystemImmunologyHerpes Simplex EncephalitisImmunologic MechanismImmune System +18

Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection

Martin K. Thomsen, Ramya Nandakumar, Daniela Stadler, +9

Hepatology

STEEP mediates STING ER exit and activation of signaling

Bao‐cun Zhang, Ramya Nandakumar, Line S. Reinert, +28

Nature Immunology

Signal TransductionIntercellular CommunicationCellular BiochemistryMedicineCell Biology +2

Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling

Ramya Nandakumar, Roland Tschismarov, Felix Meissner, +17

Nature Microbiology

Signal TransductionParacrine Cgas–sting SignallingMedicineBacteriologyMolecular Biology +7

A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology

Thaneas Prabakaran, Anne Troldborg, Sarinya Kumpunya, +17

EBioMedicine

An innate antiviral pathway acting before interferons at epithelial surfaces

Marie B. Iversen, Line S. Reinert, Martin K. Thomsen, +18

Nature Immunology

Molecular VirologyPathogenesisViral PathogenesisImmunologyInnate Antiviral Pathway +7

Hepatitis C Virus Replication in Mouse Cells Is Restricted by IFN-Dependent and -Independent Mechanisms

Ramya Nandakumar, Katja Finsterbusch, Christoph Lipps, +10

Gastroenterology

Viral ReplicationMolecular VirologyHepatitis CViral HepatitisViral Polymerase Mechanism +8

IRF-1 Expression Is Essential for Natural Killer Cells to Suppress Metastasis

Antje Ksienzyk, Berit Neumann, Ramya Nandakumar, +6

Cancer Research

Lung InflammationImmunologyImmune RegulationImmunoeditingImmunologic Mechanism +19

Utility of saliva and hair follicles in donor selection for hematopoietic stem cell transplantation and chimerism monitoring

Gurvinder Kaur, Neeraj Kumar, Ramya Nandakumar, +11

Chimerism

HistocompatibilityGenetic TestingElderly PatientsGeneticsGenetic Epidemiology +23