C C Bancroft

Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma.

John B. Sunwoo, Zhong Chen, Guo‐Chung Dong et al. · PubMed · 2001 · 479 citations

Chemoprevention Strategy, Squamous Cell Carcinoma, Immunology +17

Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma.

Gang Dong, Zhong Chen, Z Y Li et al. · PubMed · 2001 · 283 citations

Hnscc Cells, Immunology, Pathology +24

Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF‐κB and AP‐1 activation and IL‐8 and VEGF expression in human head and neck squamous cell carcinoma lines

C C Bancroft, Zhong Chen, Jason Yeh et al. · International Journal of Cancer · 2002 · 231 citations · Full text

IL (interleukin)-1alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas.

J. Wolf, Zhong Chen, Guo‐Chung Dong et al. · PubMed · 2001 · 215 citations

Immunology, Pathology, Cancer Biology +19

Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappaB signal pathways.

C C Bancroft, Zhong Chen, Gang Dong et al. · PubMed · 2001 · 178 citations

Immunology, Pathology, Ikk-nf-kappab Signal Pathways +17