L H Augenlicht

Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines.

Barbara G. Heerdt, M A Houston, L H Augenlicht · PubMed · 1994 · 359 citations

Biochemistry, Colonic Cell Differentiation, Medicine +15

Short-chain fatty acid-initiated cell cycle arrest and apoptosis of colonic epithelial cells is linked to mitochondrial function.

Barbara G. Heerdt, M A Houston, L H Augenlicht · PubMed · 1997 · 181 citations

Inflammation, Mitophagy, Colonic Epithelial Cells +15

Low-level c-myc amplification in human colonic carcinoma cell lines and tumors: a frequent, p53-independent mutation associated with improved outcome in a randomized multi-institutional trial.

L H Augenlicht, Scott Wadler, George Corner et al. · PubMed · 1997 · 114 citations

Gene Amplification, Pathology, Cancer Biology +19

Expression of mitochondrial cytochrome c oxidase in human colonic cell differentiation, transformation, and risk for colonic cancer.

Barbara G. Heerdt, Heidi Halsey, Mack Lipkin et al. · PubMed · 1990 · 77 citations

Genetics, Pathology, Redox Biology +18

Dissociation of staurosporine-induced apoptosis from G2-M arrest in SW620 human colonic carcinoma cells: initiation of the apoptotic cascade is associated with elevation of the mitochondrial membrane potential (deltapsim).

Barbara G. Heerdt, Michele Houston, J M Mariadason et al. · PubMed · 2000 · 31 citations

Stsp-induced Cascades, Chemoprevention Strategy, Lipid Peroxidation +21