Emma M. Briggs

Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing

Emma M. Briggs, Federico Rojas, Richard McCulloch et al. · Nature Communications · 2021 · 75 citations · Full text

Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei

Jennifer Ann Stortz, Tiago D. Serafim, Sam Alsford et al. · PLoS Pathogens · 2017 · 59 citations · Full text

Genetics, Genomic Mechanism, Molecular Biology +19

Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion

Emma M. Briggs, Kathryn Crouch, Leandro Lemgruber et al. · PLoS Genetics · 2018 · 54 citations · Full text

Reverse Genetics, Genetics, Immunology +17

Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection

Juan F. Quintana, Praveena Chandrasegaran, Matthew C. Sinton et al. · Nature Communications · 2022 · 45 citations · Full text

Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome

Emma M. Briggs, Graham Hamilton, Kathryn Crouch et al. · Nucleic Acids Research · 2018 · 44 citations · Full text

Conserved Localization, Genetics, Molecular Biology +23