Targeting and activation of Rac1 are mediated by the exchange factor β-Pix

Jean Paul ten Klooster, Zahara M. Jaffer, Jonathan Chernoff, +1

The Journal of Cell Biology

p21-Activated Kinase 5 (Pak5) Localizes to Mitochondria and Inhibits Apoptosis by Phosphorylating BAD

Sophie Cotteret, Zahara M. Jaffer, Alexander Beeser, +1

Molecular and Cellular Biology

Inhibits ApoptosisApoptosisCell DeathMolecular BiologyOxidative Stress +19

p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model

Hoi Yee Chow, Adrian M. Jubb, Jennifer N. Koch, +10

Cancer Research

Tumor RegressionRas GenesDermatologyCancer BiologyTumor Biology +15

Role of Group A p21-activated Kinases in Activation of Extracellular-regulated Kinase by Growth Factors

Alexander Beeser, Zahara M. Jaffer, Clemens Hofmann, +1

Journal of Biological Chemistry

Signal TransductionExtracellular-regulated KinaseSignaling PathwayCell RegulationGrowth Factor +13

Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes

Kai Mao, Satoru Kobayashi, Zahara M. Jaffer, +4

Journal of Molecular and Cellular Cardiology

Cardiac MuscleCardiomyopathyMolecular PhysiologySignal TransductionP21-activated Kinase +5

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

Jayme D. Allen, Zahara M. Jaffer, Su-Jung Park, +13

Blood

Regulation of protein tyrosine phosphatase 1B by sumoylation

Shrikrishna Dadke, Sophie Cotteret, Shu‐Chin Yip, +8

Nature Cell Biology

Signal TransductionBiochemistryMolecular RegulationNatural SciencesReceptor Tyrosine Kinase +5

Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases

Céline Van den Broeke, Maria Radu, Matthias Deruelle, +5

Proceedings of the National Academy of Sciences

Viral ReplicationMolecular BiologyCytoskeletonViral Structural ProteinVirus Structure +19

Essential role of CIB1 in regulating PAK1 activation and cell migration

Mingjuan Liu, Zahara M. Jaffer, Jonathan Chernoff, +1

The Journal of Cell Biology

PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics

Stephen D. Smith, Zahara M. Jaffer, Jonathan Chernoff, +1

Journal of Cell Science

Signal TransductionPak1-null MiceTumor MicroenvironmentSignaling PathwayCell Regulation +13