Uriel López-Sánchez

Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

Andrea Legati, Donatella Giovannini, Gaël Nicolas et al. · Nature Genetics · 2015 · 306 citations · Full text

Neurodegenerative Diseases, Altered Phosphate Export, Mendelian Disorder +6

Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM

Tomasz Uchański, Simonas Masiulis, Baptiste Fischer et al. · Nature Methods · 2021 · 146 citations · Full text

Protein Structure Determination, Protein Assembly, Biomolecular Structure Prediction +13

XPR1 mutations are a rare cause of primary familial brain calcification

Mathieu Anheim, Uriel López-Sánchez, Donatella Giovannini et al. · Journal of Neurology · 2016 · 74 citations · Full text

Rare Cause, Mendelian Disorder, Neurological Disorder +11

Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis

Uriel López-Sánchez, Sandrine Tury, Gaël Nicolas et al. · Journal of Biological Chemistry · 2020 · 69 citations · Full text

Ligand binding initiates single-molecule integrin conformational activation

Jing Li, Myung Hyun Jo, Jiabin Yan et al. · Cell · 2024 · 50 citations · Full text