Laura D. Hamel

Mutations in the X-linked Intellectual Disability Gene, zDHHC9, Alter Autopalmitoylation Activity by Distinct Mechanisms

David A. Mitchell, Laura D. Hamel, Krishna D. Reddy et al. · Journal of Biological Chemistry · 2014 · 65 citations · Full text

Alter Autopalmitoylation Activity, Distinct Mechanisms, Mendelian Disorder +10

The Erf4 Subunit of the Yeast Ras Palmitoyl Acyltransferase Is Required for Stability of the Acyl-Erf2 Intermediate and Palmitoyl Transfer to a Ras2 Substrate

David A. Mitchell, Laura D. Hamel, Kayoko Ishizuka et al. · Journal of Biological Chemistry · 2012 · 46 citations · Full text

Biosynthesis, Biochemistry, Ras2 Substrate +7

A fluorescence-based assay to monitor autopalmitoylation of zDHHC proteins applicable to high-throughput screening

Laura D. Hamel, Robert J. Deschenes, David A. Mitchell · Analytical Biochemistry · 2014 · 31 citations · Full text

Protein Function, Protein Expression, Zdhhc Proteins +10

Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library

Laura D. Hamel, Brian Lenhart, David A. Mitchell et al. · Combinatorial Chemistry & High Throughput Screening · 2016 · 23 citations · Full text

Drug Target, Biomolecular Structure Prediction, Molecular Biology +17