J.A. Clarkson-Jones

Metabolic disposition of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, in rat, dog and man

D. McKillop, Michael G. Hutchison, E. A. Partridge et al. · Xenobiotica · 2004 · 130 citations

Pharmacy, Pharmacokinetics, Pharmacology +11

Assessment of the Mass Balance Recovery and Metabolite Profile of Avibactam in Humans and In Vitro Drug-Drug Interaction Potential

Karthick Vishwanathan, Stuart Mair, Anshul Gupta et al. · Drug Metabolism and Disposition · 2014 · 51 citations

Medicine, Pharmacokinetics, Pharmacology +16

Evaluation of the use of UPLC-TOFMS with simultaneous [14C]-radioflow detection for drug metabolite profiling: Application to propranolol metabolites in rat urine

Toby J. Athersuch, R.L. Sison, A.S.J. Kenyon et al. · Journal of Pharmaceutical and Biomedical Analysis · 2008 · 19 citations

Life Sciences, Pharmaceutical Analysis, Pharmacology +9

The metabolism of [14C]-zibotentan (ZD4054) in rat, dog and human, the loss of the radiolabel and the identification of an anomalous peak, derived from the animal feed

Eva M. Lenz, A.S.J. Kenyon, Scott Martin et al. · Journal of Pharmaceutical and Biomedical Analysis · 2011 · 14 citations

Medicine, Pharmacokinetics, Pharmacology +6

405 A mass balance study to investigate the metabolism, excretion and pharmacokinetics of [14C]-olaparib (AZD2281) in patients with advanced solid tumours refractory to standard treatments

Joo Ern Ang, J.A. Clarkson-Jones, Helen Swaisland et al. · European Journal of Cancer Supplements · 2010 · 12 citations

Medicine, Pharmacokinetics, Pharmacology +8