Duncan Laverty

GABAA receptor signalling mechanisms revealed by structural pharmacology

Simonas Masiulis, Rooma Desai, Tomasz Uchański et al. · Nature · 2018 · 538 citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +7

Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer

Duncan Laverty, Rooma Desai, Tomasz Uchański et al. · Nature · 2018 · 332 citations · Full text

Proteinlipid Interaction, Molecular Physiology, Biochemistry +11

Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites

Duncan Laverty, Philip Thomas, Martin J. Field et al. · Nature Structural & Molecular Biology · 2017 · 176 citations · Full text

Molecular Neuroscience, Neurotransmitter, Receptor (Biochemistry) +6

Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function

Heidi C. O’Neill, Duncan Laverty, Natalie E. Patzlaff et al. · Pharmacology Biochemistry and Behavior · 2012 · 26 citations · Full text

Medicine, Synaptic Transmission, Physiology +8

Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State

Zaineb Fourati, Reinis R. Ruza, Duncan Laverty et al. · Journal of Biological Chemistry · 2016 · 20 citations · Full text

Molecular Pharmacology, Signal Transduction, Molecular Physiology +9