Yusuke Tominari

The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice

Aisha Yesbolatova, Yuichiro Saito, Naomi Kitamoto et al. · Nature Communications · 2020 · 531 citations · Full text

C-terminal Fragment of Presenilin Is the Molecular Target of a Dipeptidic γ-Secretase-specific Inhibitor DAPT (N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-Butyl Ester)

Yuichi Morohashi, Toshiyuki Kan, Yusuke Tominari et al. · Journal of Biological Chemistry · 2006 · 184 citations · Full text

Sulindac Sulfide Is a Noncompetitive γ-Secretase Inhibitor That Preferentially Reduces Aβ42 Generation

Yasuko Takahashi, Ikuo Hayashi, Yusuke Tominari et al. · Journal of Biological Chemistry · 2003 · 179 citations · Full text

Solid-phase synthesis of photoaffinity probes: highly efficient incorporation of biotin-tag and cross-linking groups

Toshiyuki Kan, Yusuke Tominari, Yuichi Morohashi et al. · Chemical Communications · 2003 · 34 citations

Cross-linking Groups, Solid-phase Synthesis, Photoaffinity Probes +15

Parallel synthesis of DAPT derivatives and their γ-secretase-inhibitory activity

Toshiyuki Kan, Yusuke Tominari, Kentaro Rikimaru et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 29 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +5