Interaction of Epstein-Barr Virus Nuclear Antigen Leader Protein (EBNA-LP) with HS1-Associated Protein X-1: Implication of Cytoplasmic Function of EBNA-LP

Yasushi Kawaguchi, Kaori Nakajima, Mie Igarashi, +8

Journal of Virology

Ebv-induced TransformationViral ReplicationEbna-lp CdnaCell RegulationEpstein-barr Virus +12

Epstein–Barr virus-encoded protein kinase BGLF4 mediates hyperphosphorylation of cellular elongation factor 1δ (EF-1δ): EF-1δ is universally modified by conserved protein kinases of herpesviruses in mammalian cells

Kentaro Kato, Yasushi Kawaguchi, Michiko Tanaka, +10

Journal of General Virology

Epstein‐Barr Virus (EBV) Nuclear Antigen Leader Protein (EBNA‐LP) Forms Complexes with a Cellular Anti‐Apoptosis Protein Bcl‐2 or Its EBV Counterpart BHRF1 through HS1‐Associated Protein X‐1

Go Matsuda, Kaori Nakajima, Yasushi Kawaguchi, +2

Microbiology and Immunology

Identification of Major Phosphorylation Sites of Epstein-Barr Virus Nuclear Antigen Leader Protein (EBNA-LP): Ability of EBNA-LP To Induce Latent Membrane Protein 1 Cooperatively with EBNA-2 Is Regulated by Phosphorylation

Akihiko Yokoyama, Michiko Tanaka, Go Matsuda, +8

Journal of Virology

Structure and interactions with RNA of the N-terminal UUAG-specific RNA-binding domain of hnRNP D0

Takashi Nagata, Yasuyuki Kurihara, Go Matsuda, +6

Journal of Molecular Biology

EngineeringNatural SciencesRna Binding ProteinsRna Structure PredictionRna Biology +5

Herpes simplex virus 1 α regulatory protein ICP0 functionally interacts with cellular transcription factor BMAL1

Yasushi Kawaguchi, Michiko Tanaka, Akihiko Yokoymama, +5

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyMolecular BiologyIcp0-null MutantTranscriptional Regulation +16

Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA

Masato Katahira, Yohei Miyanoiri, Yoshiaki Enokizono, +4

Journal of Molecular Biology

Backbone DynamicsBiochemistryNatural SciencesRna Binding ProteinsRna Structure Prediction +8

Crystal Structure of Human Importin-α1 (Rch1), Revealing a Potential Autoinhibition Mode Involving Homodimerization

Hideyuki Miyatake, Akira Sanjoh, Satoru Unzai, +5

PLoS ONE

Crystal StructureProtein AssemblyMolecular BiologyHuman Importin-α1Analytical Ultracentrifugation +14

A Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro

Kenichiro Motomura, Naoko Okada, Hideaki Morita, +11

PLoS ONE

Pctb DifferentiationCell CultureCell ProliferationPka ActivationEmbryology +19

Inhibition of human immunodeficiency virus type 1 (HIV-1) nuclear import via Vpr–Importin α interactions as a novel HIV-1 therapy

Tatsunori Suzuki, Norio Yamamoto, Mizuho Nonaka, +9

Biochemical and Biophysical Research Communications

Nuclear ImportNovel Hiv-1 TherapyMedicineHuman RetrovirusImmunology +10