Kaoru Nakao

Involvement of central μ-opioid system in the scratching behavior in mice, and the suppression of it by the activation of κ-opioid system

Hideo Umeuchi, Yuko Togashi, Toshiyuki Honda et al. · European Journal of Pharmacology · 2003 · 146 citations

Behavioral Neuroscience, Medicine, Behavioural Pharmacology +11

Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration

Hiroshi Nagase, Toru Nemoto, Ayaka Matsubara et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 78 citations · Full text

Molecular Pharmacology, Functional Selectivity, Medicine +10

Nalfurafine hydrochloride: A new drug for the treatment of uremic pruritus in hemodialysis patients

Kaoru Nakao, Hidenori Mochizuki · Drugs of today · 2009 · 68 citations

New Drug, Hemodialysis, Urology +10

Endogenous opioids and related peptides: from molecular biology to clinical medicine The Sir Henry Dale Lecture for 1985

Hiroo Imura, Yoshihisa Kato, Y Nakai et al. · Journal of Endocrinology · 1985 · 59 citations

Opioid Epidemic, Molecular Biology, Pharmacotherapy +21

Drug design and synthesis of a novel κ opioid receptor agonist with an oxabicyclo[2.2.2]octane skeleton and its pharmacology

Hiroshi Nagase, Akio Watanabe, Toru Nemoto et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 34 citations · Full text

Molecular Pharmacology, Biochemistry, Drug Design +8