Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

Ellis Chika Onwordi, Els F. Halff, Thomas Whitehurst, +13

Nature Communications

Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease

Oliver Wirths, Henning Breyhan, Andrea Marcello, +3

Neurobiology of Aging

InflammationAlzheimer's DiseaseMedicineDementiaInflammatory Changes +10

Transient intraneuronal Aβ rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice

Ditte Z. Christensen, Sophie L. Kraus, Antonius Flohr, +3

Acta Neuropathologica

Transient Intraneuronal AβSynaptic SignalingTau ProteinSocial SciencesFrontal Cortex +16

Selective Remediation of Reversal Learning Deficits in the Neurodevelopmental MAM Model of Schizophrenia by a Novel mGlu5 Positive Allosteric Modulator

François Gastambide, Marie-Caroline Côtel, Gary Gilmour, +3

Neuropsychopharmacology

NeuropsychologyPsychiatryDevelopmental Cognitive NeuroscienceNeurodevelopmental Mam ModelMedicine +10

Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice

Marie-Caroline Côtel, Sadim Jawhar, Ditte Z. Christensen, +2

Neurobiology of Aging

Memory DeficitsDevelopmental BiologyCortical RemodelingNeurogenesisEnvironmental Enrichment +5

Microglial activation in the rat brain following chronic antipsychotic treatment at clinically relevant doses

Marie-Caroline Côtel, Ewelina M. Lenartowicz, Sridhar Natesan, +5

European Neuropsychopharmacology

Relevant DosesPsychiatryMicroglial ActivationMedicineNeuropharmacology +9

Alterations in hippocampal excitability, synaptic transmission and synaptic plasticity in a neurodevelopmental model of schizophrenia

Thomas M. Sanderson, Marie-Caroline Côtel, Michael J. O’Neill, +3

Neuropharmacology

Neurodevelopmental DisordersSynaptic PlasticityPsychiatryDevelopmental Cognitive NeuroscienceBrain Development +13

The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells

Rodrigo R. R. Duarte, Nathaniel D. Bachtel, Marie-Caroline Côtel, +13

Biological Psychiatry

Age-dependent loss of dentate gyrus granule cells in APP/PS1KI mice

Marie-Caroline Côtel, Thomas A. Bayer, Oliver Wirths

Brain Research

Lifespan ExtensionKnockout MouseMolecular NeuroscienceAgingDegenerative Pathology +7

Effects of chronic antipsychotic drug exposure on the expression of Translocator Protein and inflammatory markers in rat adipose tissue

Anita Calevro, Marie-Caroline Côtel, Sridhar Natesan, +3

Psychoneuroendocrinology

ObesityMetabolic SyndromeRat Adipose TissuePsychoactive DrugTranslocator Protein +7