Christophe Giraudon

Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells

Gema Santamaría Núñez, Carlos Mario Genes Robles, Christophe Giraudon et al. · Molecular Cancer Therapeutics · 2016 · 153 citations

Life Sciences, Molecular Biology, Oncology +17

ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activities

Wassim Abdulrahman, Izarn Iltis, Laura Radu et al. · Proceedings of the National Academy of Sciences · 2013 · 84 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Temperature-induced melting of double-stranded DNA in the absence and presence of covalently bonded antitumour drugs: insight from molecular dynamics simulations

Juan A. Bueren‐Calabuig, Christophe Giraudon, Carlos M. Galmarini et al. · Nucleic Acids Research · 2011 · 67 citations · Full text

Natural Sciences, Biophysics, Chemistry +17

XPF-Dependent DNA Breaks and RNA Polymerase II Arrest Induced by Antitumor DNA Interstrand Crosslinking-Mimetic Alkaloids

Sascha Feuerhahn, Christophe Giraudon, Marta Martínez et al. · Chemistry & Biology · 2011 · 48 citations

Life Sciences, Molecular Biology, Oncology +16

XPD mutations in trichothiodystrophy hamper collagen VI expression and reveal a role of TFIIH in transcription derepression

Donata Orioli, Emmanuel Compe, Tiziana Nardò et al. · Human Molecular Genetics · 2012 · 27 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15