Andrea C. Florian

WIN site inhibition disrupts a subset of WDR5 function

Andrew J. Siladi, Jing Wang, Andrea C. Florian et al. · Scientific Reports · 2022 · 38 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells

Andrea C. Florian, Chase M. Woodley, Jing Wang et al. · NAR Cancer · 2022 · 18 citations · Full text

Medicine, Cancer Biology, Oncology +17

Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

Gregory C. Howard, Jing Wang, Kristie L. Rose et al. · eLife · 2023 · 18 citations · Full text

Medicine, Molecular Biology, Oncology +14

The SWI/SNF ATPase BRG1 facilitates multiple pro-tumorigenic gene expression programs in SMARCB1-deficient cancer cells

Kylie C. Moe, Jack N. Maxwell, Jing Wang et al. · Oncogenesis · 2022 · 14 citations · Full text

Medicine, Cancer Biology, Oncology +17