SAMHD1 acts at stalled replication forks to prevent interferon induction

Flavie Coquel, Maria João Silva, Hervé Técher, +18

Nature

Natural SciencesGeneticsStalled Replication ForksDna ReplicationMolecular Biology +2

A mechanism for preventing asymmetric histone segregation onto replicating DNA strands

Chuanhe Yu, Haiyun Gan, Albert Serra‐Cardona, +7

Science

Polyphosphate is involved in cell cycle progression and genomic stability in <i>Saccharomyces cerevisiae</i>

Samuel Bru, Joan Marc Martínez‐Láinez, Sara Hernández‐Ortega, +8

Molecular Microbiology

Polyp MutantsGeneticsMolecular BiologyMolecular GeneticsCell Cycle +15

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Xuanxuan Xing, Daniel P. Kane, Chelsea R. Bulock, +4

Nature Communications

Sphingolipid Biosynthetic Pathway Genes <i>FEN1</i> and <i>SUR4</i> Modulate Amphotericin B Resistance

Sushma Sharma, Alfatah, Vinay Kumar Bari, +3

Antimicrobial Agents and Chemotherapy

Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress

Haiyun Gan, Chuanhe Yu, Sujan Devbhandari, +5

Molecular Cell

ChromatinGenome InstabilityNatural SciencesMolecular BiologyDna Replication +5

Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage

Julien Bacal, María Moriel‐Carretero, Benjamin Pardo, +5

The EMBO Journal

ChromatinGenome InstabilityTranscriptional RegulationDna DamageChromatin Remodeling +8

Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication

Romain Forey, Ana Poveda, Sushma Sharma, +10

Molecular Cell

ChromatinGenome InstabilityCell RegulationNatural SciencesMolecular Biology +6

Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity

Tony M. Mertz, Sushma Sharma, Andrei Chabes, +1

Proceedings of the National Academy of Sciences

Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools

Amitabha Gupta, Sushma Sharma, Patrick Reichenbach, +6

Genetics

GeneticsGenomic MechanismMolecular BiologyModest ShorteningCellular Physiology +15