Gokulakrishnan Seshadri

Sustained release of a p38 inhibitor from non-inflammatory microspheres inhibits cardiac dysfunction

Jay C. Sy, Gokulakrishnan Seshadri, Stephen C. Yang et al. · Nature Materials · 2008 · 121 citations · Full text

Inflammation, Sustained Release, Heart Failure +11

The delivery of superoxide dismutase encapsulated in polyketal microparticles to rat myocardium and protection from myocardial ischemia-reperfusion injury

Gokulakrishnan Seshadri, Jay C. Sy, Milton E. Brown et al. · Biomaterials · 2009 · 94 citations

Cell-based Drug Delivery, Nanomedicine, Engineering +10

Epigenetic silencing of genes enhanced by collective role of reactive oxygen species and MAPK signaling downstream ERK/Snail axis: Ectopic application of hydrogen peroxide repress CDH1 gene by enhanced DNA methyltransferase activity in human breast cancer

Nibedita Pradhan, Sabnam Parbin, Swayamsiddha Kar et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2019 · 67 citations

Epigenetic Silencing, Chromatin, Systems Biology +8

Acute Preconditioning of Cardiac Progenitor Cells with Hydrogen Peroxide Enhances Angiogenic Pathways Following Ischemia-Reperfusion Injury

Karl D. Pendergrass, Archana V. Boopathy, Gokulakrishnan Seshadri et al. · Stem Cells and Development · 2013 · 53 citations

Heart Failure, Cardiac Progenitor Cells, Redox Biology +20

Characterization of Superoxide Dismutases in Cardiac Progenitor Cells Demonstrates a Critical Role for Manganese Superoxide Dismutase

Gokulakrishnan Seshadri, Pao Lin, Archana V. Boopathy et al. · Stem Cells and Development · 2012 · 13 citations · Full text

Cardiac Muscle, Heart Failure, Lipid Peroxidation +20