Joseph Cahiwat

A small-molecule inhibitor of the Wnt pathway (SM04690) as a potential disease modifying agent for the treatment of osteoarthritis of the knee

V. Deshmukh, Haide Hu, Charlene F. Barroga et al. · Osteoarthritis and Cartilage · 2017 · 223 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Modulation of the Wnt pathway through inhibition of CLK2 and DYRK1A by lorecivivint as a novel, potentially disease-modifying approach for knee osteoarthritis treatment

V. Deshmukh, Alyssa L. O'Green, Carine Bossard et al. · Osteoarthritis and Cartilage · 2019 · 193 citations · Full text

Medicine, Orthopaedic Surgery, Pharmacology +17

The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models

Betty Y. Tam, Kevin Chiu, Heekyung Chung et al. · Cancer Letters · 2019 · 143 citations · Full text

Medicine, Oncology, Pharmacology +17