Xi-Chen Zhu

Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease

Teng Jiang, Lan Tan, Xi-Chen Zhu et al. · Neuropsychopharmacology · 2014 · 323 citations · Full text

Transgenic Mouse Model, Trem2 Ameliorates Neuropathology, Alzheimer ’ +18

TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice

Teng Jiang, Yingdong Zhang, Qi Chen et al. · Neuropharmacology · 2016 · 173 citations

Inflammation, Neurodegenerative Diseases, Medicine +10

A rare coding variant in TREM2 increases risk for Alzheimer's disease in Han Chinese

Teng Jiang, Lan Tan, Qi Chen et al. · Neurobiology of Aging · 2016 · 133 citations

Alzheimer's Disease, Genetics, Dementia +11

Silencing of TREM2 exacerbates tau pathology, neurodegenerative changes, and spatial learning deficits in P301S tau transgenic mice

Teng Jiang, Lan Tan, Xi-Chen Zhu et al. · Neurobiology of Aging · 2015 · 113 citations

Knockout Mouse, Neurodegenerative Diseases, Neurodegenerative Changes +9

Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice

Teng Jiang, Jin‐Tai Yu, Xi-Chen Zhu et al. · Neurobiology of Aging · 2013 · 99 citations

Alzheimer's Disease, Aging, Longevity +10