Heleen Kool

Sox2 Regulates the Emergence of Lung Basal Cells by Directly Activating the Transcription of <i>Trp63</i>

Joshua K. Ochieng, Kim Schilders, Heleen Kool et al. · American Journal of Respiratory Cell and Molecular Biology · 2014 · 95 citations

Life Sciences, Developmental Biology, Genetics +17

Clinically relevant timing of antenatal sildenafil treatment reduces pulmonary vascular remodeling in congenital diaphragmatic hernia

Daphne S. Mous, Heleen Kool, Marjon J. Buscop-van Kempen et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2016 · 41 citations

Medicine, Pharmacology, Pharmacotherapy +16

Treatment of rat congenital diaphragmatic hernia with sildenafil and NS-304, selexipag’s active compound, at the pseudoglandular stage improves lung vasculature

Daphne S. Mous, Heleen Kool, Petra E. Bürgisser et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2018 · 31 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Inhibition of retinoic acid signaling induces aberrant pericyte coverage and differentiation resulting in vascular defects in congenital diaphragmatic hernia

Heleen Kool, Petra E. Bürgisser, Gabriëla G. Edel et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2019 · 22 citations · Full text

Life Sciences, Developmental Biology, Physiology +17

Endothelial loss of Fzd5 stimulates PKC/Ets1-mediated transcription of Angpt2 and Flt1

Maarten M. Brandt, Chris Van Dijk, Ihsan Chrifi et al. · Angiogenesis · 2018 · 21 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16