Stephanie L. James

IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages

Ricardo T. Gazzinelli, Isabelle P. Oswald, Stephanie L. James et al. · The Journal of Immunology · 1992 · 698 citations · Full text

The microbicidal activity of interferon‐γ‐treated macrophages against <i>Trypanosoma cruzi</i> involves an L‐arginine‐dependent, nitrogen oxide‐mediated mechanism inhibitable by interleukin‐10 and transforming growth factor‐β

Ricardo T. Gazzinelli, Isabelle P. Oswald, Sara Hieny et al. · European Journal of Immunology · 1992 · 434 citations

Microbial Pathogens, Antiparasitic Agent, Innate Immune System +24

IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity

Isabelle P. Oswald, Ricardo T. Gazzinelli, Alan Sher et al. · The Journal of Immunology · 1992 · 416 citations · Full text

Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation.

Isabelle P. Oswald, Thomas A. Wynn, Alan Sher et al. · Proceedings of the National Academy of Sciences · 1992 · 348 citations

Macrophage Activation, Interferon Gamma-induced Activation, Immune Regulation +21

Induction of protective immunity against Schistosoma mansoni by vaccination with schistosome paramyosin (Sm97), a nonsurface parasite antigen.

Edward J. Pearce, Stephanie L. James, Sara Hieny et al. · Proceedings of the National Academy of Sciences · 1988 · 225 citations · Full text

Schistosoma Mansoni, Parasitic Disease, Microbial Pathogens +16