Guan‐Jun Yang

A small molecule HIF-1α stabilizer that accelerates diabetic wound healing

Guodong Li, Chung-Nga Ko, Dan Li et al. · Nature Communications · 2021 · 244 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Selective Inhibition of Lysine‐Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple‐Negative Breast Cancer Therapy

Guan‐Jun Yang, Wanhe Wang, Simon Wing Fai Mok et al. · Angewandte Chemie International Edition · 2018 · 169 citations

Medicine, Medicinal Chemistry, Molecular Biology +17

Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines

Guan‐Jun Yang, Chung-Nga Ko, Hai‐Jing Zhong et al. · Cancers · 2019 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Identification of a rhodium(<scp>iii</scp>) complex as a Wee1 inhibitor against<i>TP53</i>-mutated triple-negative breast cancer cells

Guan‐Jun Yang, Hai‐Jing Zhong, Chung-Nga Ko et al. · Chemical Communications · 2018 · 63 citations

Medicine, Medicinal Chemistry, Oncology +13

Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer

Shasha Cheng, Yuan Qing Qu, Jia Wu et al. · Acta Pharmaceutica Sinica B · 2021 · 58 citations · Full text

Life Sciences, Medicinal Chemistry, Oncology +17