Chris A. Brackley

Nonspecific bridging-induced attraction drives clustering of DNA-binding proteins and genome organization

Chris A. Brackley, Stephen Taylor, Argyris Papantonis et al. · Proceedings of the National Academy of Sciences · 2013 · 305 citations · Full text

HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types

Anne Zirkel, Miloš Nikolić, Konstantinos Sofiadis et al. · Molecular Cell · 2018 · 236 citations · Full text

Genome Instability, Cell Types, Cell Regulation +8

Simulated binding of transcription factors to active and inactive regions folds human chromosomes into loops, rosettes and topological domains

Chris A. Brackley, James Johnson, Steven Kelly et al. · Nucleic Acids Research · 2016 · 208 citations · Full text

Genetics, Molecular Biology, Gene Regulatory Network +22

Polymer Simulations of Heteromorphic Chromatin Predict the 3D Folding of Complex Genomic Loci

Adam Buckle, Chris A. Brackley, Shelagh Boyle et al. · Molecular Cell · 2018 · 204 citations · Full text

Nonequilibrium Chromosome Looping via Molecular Slip Links

Chris A. Brackley, James Johnson, Davide Michieletto et al. · Physical Review Letters · 2017 · 136 citations · Full text