Ya Guo

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

Ya Guo, Quan Xu, Daniele Canzio et al. · Cell · 2015 · 1K citations · Full text

Transcriptional Regulation, Natural Sciences, Genetics +10

CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice

Ya Guo, Kevin D. Monahan, Haiyang Wu et al. · Proceedings of the National Academy of Sciences · 2012 · 271 citations · Full text

Neurogenomics, Molecular Regulation, Molecular Biology +20

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

Sergi Cuartero, Felix D. Weiss, Gopuraja Dharmalingam et al. · Nature Immunology · 2018 · 236 citations · Full text

Cell Lineage, Developmental Biology, Cell Specialization +10

Efficient inversions and duplications of mammalian regulatory DNA elements and gene clusters by CRISPR/Cas9

Jinhuan Li, Jia Shou, Ya Guo et al. · Journal of Molecular Cell Biology · 2015 · 151 citations · Full text

Precise Inversions, Off-target Effect, Engineering +15

Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection

Zhilian Jia, Jingwei Li, Xiao Ge et al. · Genome biology · 2020 · 83 citations · Full text