Jon C. Mirsalis

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

Margaret A. Phillips, Julie Lotharius, Kennan C. Marsh et al. · Science Translational Medicine · 2015 · 375 citations

Medicine, Pharmacology, Pharmacotherapy +9

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

Barry R. O’Keefe, Fakhrieh Vojdani, Viviana Buffa et al. · Proceedings of the National Academy of Sciences · 2009 · 264 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +8

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of <i>Plasmodium</i>

Marı́a Belén Jiménez-Dı́az, Daniel Ebert, Yandira G. Salinas et al. · Proceedings of the National Academy of Sciences · 2014 · 247 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Detection of genotoxic carcinogens in the in vivo‐in vitro hepatocyte dna repair assay

Jon C. Mirsalis, C. Kim Tyson, Byron E. Butterworth · Environmental Mutagenesis · 1982 · 194 citations

Pharmacy, Toxicology, Dna Repair +12

Measurement of unscheduled DNA synthesis and S‐phase synthesis in rodent hepatocytes following in vivo treatment: Testing of 24 compounds

Jon C. Mirsalis, C. Kim Tyson, Karen L. Steinmetz et al. · Environmental and Molecular Mutagenesis · 1989 · 192 citations

Pharmacy, Toxicology, Carcinogenesis +13